Gabexate Mesylate for Injection

[Specification] 100mg;500mg

[Indications] Gabexate mesylate for injection is a synthetic protease inhibitor indicated for the treatment of acute mild (oedematous) pancreatitis and as adjunctive treatment of acute haemorrhagic necrotising pancreatitis; it is also used in some countries for disseminated intravascular coagulation.

[Usage and dosage] The drug is for intravenous infusion only. The usual adult dose is 100 mg at a time, increased to 300 mg per day during the first three days of treatment and then reduced to 100 mg once daily, with a course lasting 6 to 10 days. The powder is dissolved in 5 mL of water for injection and diluted in 500 mL of glucose 5% or Ringer's solution; the infusion rate should be kept below 1 mg/kg per hour and must not exceed 2.5 mg/kg per hour.