Arginine Hydrochloride Injection

[Specification] 200ml: 20 g

[Indications] Arginine hydrochloride injection is indicated for the treatment of hepatic encephalopathy, particularly in patients who must avoid sodium, and for mental symptoms caused by hyperammonaemia from other causes.

[Usage and dosage] Dilute immediately before use. The usual adult dose is 15 to 20 g, equivalent to 60 to 80 mL of a 25% solution, added to 1000 mL of glucose 5% solution and infused intravenously over about 4 hours; the dose may be repeated according to the blood ammonia concentration. The solution is strongly acidic, so extravasation must be avoided, and acid-base status, potassium, and blood glucose should be monitored, particularly in patients with renal impairment.